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Safety Legal Medicine CAS 107868-30-4 Exemestane Aromasin for Men or Women Body Building

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Safety Legal Medicine CAS 107868-30-4 Exemestane Aromasin for Men or Women Body Building

China Safety Legal Medicine CAS 107868-30-4 Exemestane Aromasin for Men or Women Body Building supplier

Large Image :  Safety Legal Medicine CAS 107868-30-4 Exemestane Aromasin for Men or Women Body Building

Product Details:

Place of Origin: China
Brand Name: Grand Uni or OEM
Certification: ISO9001
Model Number: CAS:107868-30-4

Payment & Shipping Terms:

Minimum Order Quantity: 10Grams
Price: Negotiation
Packaging Details: We have several packaging methods for your choice!
Delivery Time: Around 5 days
Payment Terms: TT, West Union, and Money Gram
Supply Ability: Enough in Stock
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Detailed Product Description
Name: Exemestane Alias: Aromasin ; Exemestan;Exemestane
Product Category: Pharmaceutical Raw Materials And Intermediates MF: C20H24O2
MW: 296.40 Other Drugs In Same Class: :Anastrozole,Letrozole,Tamoxifen Citrate,Exemestane

Safety Legal Medicine CAS 107868-30-4 Exemestane Aromasin for Men or Women Body Building

 

Quick Detail:

 

Exemestane (trade name Aromasin) is a drug used to treat breast cancer. It is a member of the class of drugs known as aromatase inhibitors. Some breast cancers require estrogen to grow. Those cancers have estrogen receptors (ERs), and are called ER-positive. They may also be called estrogen-responsive, hormonally-responsive, or hormone-receptor-positive. Aromatase is an enzyme that synthesizes estrogen. Aromatase inhibitors block the synthesis of estrogen. This lowers the estrogen level, and slows the growth of cancers.

 

Description:

 

Exemestane

Alias: Aromasin ; Exemestan;Exemestane

Product Category: Pharmaceutical raw materials and intermediates

Assay: 98%min

CAS Registry Number:107868-30-4

Molecular formula: C20H24O2

Molecular Weight:296.40

Appearance: White or Almost White Crystalline Powder

Grade : Pharmaceutical Grade

Storage: Shading, confined preservation

Usage: Developed to help fight breast cancer, Aromasin is one of the most powerful estrogen suppressing compounds

Other drugs in same class:Anastrozole,Letrozole,Tamoxifen citrate,Exemestane

 

Applications:

 

1). Exemestane is an oral steroidal aromatase inhibitor that is used in ER-positive breast cancer in addition to surgery and/or radiation in post-menopausal women.

 

2). The main source of estrogen is the ovaries in premenopausal women, while in post-menopausal women most of the body's estrogen is produced via the conversion of androgens into estrogen by the aromatase enzyme in the peripheral tissues (i.e. adipose tissue like that of the breast) and a number of sites in the brain. Estrogen is produced locally via the actions of the aromatase enzyme in these peripheral tissues where it acts locally. Any circulating estrogen in post-menopausal women as well as men is the result of estrogen escaping local metabolism and entering the circulatory system.

 

3). Exemestane is an irreversible, steroidal aromatase inactivator, structurally related to the natural substrate androstenedione. It acts as a false substrate for the aromatase enzyme, and is processed to an intermediate that binds irreversibly to the active site of the enzyme causing its inactivation, an effect also known as "suicide inhibition." By being structurally similar to enzyme targets, Exemestane permanently binds to the enzymes, preventing them from converting androgen into estrogen

 

Specifications:

 

TEST ITEMS

       SPECIFICATION

RESULTS

Description

: White Crystalline Powder

White Powder

Identification

:  Positive

Positive

Assay(by HPLC)

:  98.0~102.0%

98.64%

Absorbance(E1cm)

:  465~495

482.5

Melting Point

:  191~195°C

193.5~195.0°C

Loss On Drying

:  0.5%max

0.19%

Specific Rotation

:  +288°~ +298°

+290.2°

Residue On Ignition

:  0.1%max

0.03%

Related Substances

:  Total:1.5%max

<1.3%

 

   Single:0.5%max

<0.4%

Residue Solvents

:  0.2%max

0.10%

Heavy Metals

:  20PPm max

<10PPm

 

 

 

Conclusion

The specification conform with enterprise standard.

 

Competitive Advantages:

 

1). Our company is a professional production leading factory in China in pharmaceutical area of many years,our products have exported to USA,Greece, Spain, UK, Australia and other countries, and we have got very good feedback from our customers, we had established a long friendly relations.​

 

2). High quality, best price, first-class service, high successful delivery rate.

 

3). We have stock, so we can delivery quickly at the very day when receive the payment.

 

 

 

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