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Bulk Powder Cialis Taladafil Male Enhancement Steroids 171596-29-5

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Bulk Powder Cialis Taladafil Male Enhancement Steroids 171596-29-5

China Bulk Powder Cialis Taladafil Male Enhancement Steroids 171596-29-5 supplier

Large Image :  Bulk Powder Cialis Taladafil Male Enhancement Steroids 171596-29-5

Product Details:

Place of Origin: China
Brand Name: Grand Uni or OEM
Certification: ISO9001
Model Number: CAS:171596-29-5

Payment & Shipping Terms:

Minimum Order Quantity: 10g
Price: Negotiation
Packaging Details: discreet bags
Delivery Time: 5~7 days
Payment Terms: Western Union, MoneyGram, T/T
Supply Ability: 500kg/week
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Detailed Product Description
CAS Registry Number: 171596-29-5 Assay: 99%
Appearance: White Powder Product Name: Cialis
Synonym: Tadalafil; Taladafil MF: C22H19N3O4

Bulk Powder Cialis Taladafil Male Enhancement Steroids 171596-29-5

 

Although sildenafil (Viagra), vardenafil (Levitra), and tadalafil (Cialis) all work by inhibiting PDE5, tadalafil's pharmacologic distinction is its longer half-life (17.50 hours) – compared to sildenafil and vardenafil (both 4.0–5.0 hours)– resulting in longer duration of action, and so partly responsible for "The Weekend Pill" sobriquet. Furthermore, the longer half-life is the basis for current investigation of tadalafil's daily therapeutic use in relieving pulmonary arterial hypertension. Sildenafil is approved in several world regions as a thrice-daily therapy for pulmonary arterial hypertension

 

Penile erection during sexual stimulation is caused by increased penile blood flow resulting from the relaxation of penile arteries and the smooth muscle of the corpus cavernosum. This response is mediated by the release of nitric oxide (NO) from nerve terminals and endothelial cells, which stimulates the synthesis of Cyclic guanosine monophosphate (more commonly known as Cyclic GMP or cGMP) in smooth muscle cells. cGMP relaxes smooth muscle and increases blood flow to the corpus cavernosum.

The inhibition of phosphodiesterase type 5 (PDE5) enhances erectile function by increasing the amount of cGMP. Tadalafil (and sildenafil and vardenafil) inhibits PDE5. However, because sexual stimulation is required to initiate the local penile release of nitric oxide, tadalafil's inhibition of PDE5 will have no effect without direct sexual stimulation of the penis. The recommended tadalafil starting dose for most men is 10 mg, taken as needed before sexual activity (but not more than once daily). The dose may be increased to 20 mg or decreased to 5 mg, per its efficacy and the man's personal tolerance of the drug. In June 2007, the European Commission approved low-dose (2.5 mg and 5 mg) Cialis to be used as single-daily ED therapy

 

Although available since 2003 in 5, 10, 20 mg dosage, in late 2008/early 2009, the U.S. FDA approved the commercial sale of Cialis in 2.5 mg dosage as a one-a-day treatment for ED. The 2.5 mg dose avoids earlier dispensing restrictions on higher dosages. The price of the 5 mg and 2.5 mg are often similar, so some people score and split the pill. Both physicians and the manufacturer warn against splitting the pill, especially since it is enterically coated and splitting might impact absorption.

 

Moreover, tadalafil (Adcirca) 40 mg was approved in 2009 in the United States and Europe (and 2010 in Canada and Japan) as a once-daily therapy to improve exercise ability in patients with pulmonary arterial hypertension. In patients with pulmonary arterial hypertension, the pulmonary vascular lumen is decreased as a result of vasoconstriction and vascular remodeling, resulting in increased pulmonary artery pressure and pulmonary vascular resistance. Tadalafil is believed to increase pulmonary artery vasodilation, and inhibit vascular remodeling, thus lowering pulmonary arterial pressure and pulmonary vascular resistance. Right heart failure is the principal consequence of pulmonary arterial hypertension.

On October 6, 2011, the U.S. FDA approved tadalafil to treat the signs and symptoms of benign prostatic hyperplasia (BPH). BPH is a condition in males in which the prostate gland becomes enlarged, obstructing the free flow of urine. Symptoms may include sudden urges to urinate (urgency), difficulty in starting urination (hesitancy), a weak urine stream, and more frequent urination - especially at night. The FDA has also approved tadalafil for treatment of both BPH and erectile dysfunction (ED) where the two conditions co-exist.

 

Cialis
Product name: Cialis
Synonym: Tadalafil; Taladafil
CAS Registry Number: 171596-29-5
Molecular Formula:  C22H19N3O4
Molecular Weight: 389.4
Assay: 99%
Packing: 1kg/aluminum foil bag
Appearance: White powder

Bulk Powder Cialis Taladafil Male Enhancement Steroids 171596-29-5Bulk Powder Cialis Taladafil Male Enhancement Steroids 171596-29-5

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