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|Synonyms:||Peg-Mgf 2mg/vial||Appearence:||White Powder|
|HS Code:||56786578||Package:||2mg/Vials, 10 Vials/Box|
|Appearance:||White Powder||Delivery Time:||Within 24 Hours Upon Receipt Of Payment|
|Other Name:||Pegylated Mechano|
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Pegylated Mechano Growth Injectable Peptide Hormones Powder Bodybuilding Peg-Mgf 2mg/vial
PEG MGF Basic Info.
Function: Promotion Development Dosage
Active Substance: It is PEGylated MGF
Application: PEGylation is the act of attaching a Polyethylene glycol (PEG) structure to another larger molecule (in this case, (MGF). The PEG acts as a protective coating and the theory here is that this will allow the MGF to be carried through the blood stream without being broken down.
PEG MGF Description:
Mechano Growth Factor (MGF) also known as IGF-1Ec is a growth factor/repair factor that is derived from exercised or damaged muscle tissue, Its called MGF as IGF-1Ec is a bit of a mouthful and harder to identify amongst the other igf variants.
What makes MGF special is its unique role in muscle growth.
MGF has the ability to cause wasted tissue to grow and improve itself by activating muscle stem cells and increasing the upregulation of protein synthesis, this unique ability can rapidly improve recovery and speed up muscle growth.
MGF can initiate muscle satellite (stem) cell activation in addition to its IGF-Ireceptor domain which ithen in turn ncreases protein synthesis turnover, and therefore can if used correctly improve muscle mass over time.
The liver produces 2 kinds of MGF splice variants of igf..
1) IGF-1Ec This is the first phase release igf splice variant and it appears to stimulate satellite cells into activation, This is the closest variant to synthetic MGF.
2) liver type IGF-IEa this is the secondary release of igf from the liver, and its far less anabolic.
MGF differs from the second variant IGF-IEa as it has a different peptide sequence which is responsible for replenishing the satellite cells in skeletal muscle, in other words it is more anabolic and longer acting than the systematic release of the second MGF liver variant.
So just think of MGF as a highly anabolic variant of igf. After you have trained, the IGF-I gene is spliced towards MGF then that causes hypertrophy and repair of local muscle damage by activating the muscle stem cells as well as other important anabolic processes, including the above mentioned protein synthesis, and increased nitrogen retention.
In rats some studies have shown muscle mass increases of 20 percent from a single mgf injection.. somewhow i think many of these studies are not accurate, however the potential is undeniable.
PEG MGF Usage:
Mechano Factor (MGF) exhibits local effects in skeletal muscle and without cannot travel through the body without modification. The problem with synthetic Mechano Factor (MGF) is that it is introduced intramuscularly and is water based so it goes into the blood stream. When used this way, Mechano Factor (MGF) only remains stable in the blood stream for a few minutes. Biologically produced MGF is made locally and does not enter the bloodstream.
It is also short acting so stability is not an issue. By PEGylating the Mechano Factor (MGF) it is almost as efficient as local produced Mechano Factor (MGF) when used intramuscularly. This is accomplished by surrounding part of the peptide with a structure of polyethylene glycol, which can be attached to a protein molecule. The polyethylene glycol groups protect the peptide but do not surround it completely. The active sites of the peptide are still free to do their biological function. In this case the shell is a negative charged shield against positively charged compounds that would affect the protein
PEG MGF Dosage:
Typical dosage of PEG-MGF is between 200mcg. - 400mcg. per week but many bodybuilders have said to "research" this peptide at dosages exceeding 1,500 mcg weekly with no adverse effects.
Because PEG MGF can cause site specific muscle growth, it is recommended to inject PEG MGF bi-laterally to ensure symmetrical gains. The most effective test results were experienced in users injecting the PEG MGF post exercise.
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