CAS 434-07-1 Anti Estrogen Bodybuilding Supplements Clomid Clomiphene Citrate

CAS 434-07-1 Anti Estrogen Bodybuilding Supplements Clomid Clomiphene Citrate

Quick Detail :

Another name:2-4-[2-Chloro-1,2-diphenylethenyl]phenoxy-N,N-diethylethanamine citrate 
Structural formula: C26H28ClNO C6H8O7
Molecular weight: 598.11 
CAS: 50-41-9
Appearance: white or milky white crystalline powder
Use: the goods to anti-estrogen fertility inducer, the objects in dysfunctional uterine bleeding, polycystic ovary, menstrual disorders and drug-induced amenorrhea and other gynecologic diseases
Standard: CP USP

Description:

Clomid is the anti-estrogen of choice for improving recovery of natural testosterone production after a cycle, improving testosterone production of endurance athletes, and is also effective in reducing risk of gynecomastia during a cycle employing aromatizable steroids. Clomiphene citrate stimulates the body's own production of testosterone. Clomiphene citrate comes as a pill easily administered by mouth. Clomiphene citrate has little side-effects and low risk of developing these side-effects.

Clomid is a mixed estrogen agonist/antagonist (activator/blocker) which, when bound to the estrogen receptor, puts it in a somewhat different conformation (shape) than does estradiol. The estrogen receptor requires binding of an estrogen or drug at its binding site and also the binding of any of several cofactors at different sites. Without the binding of the cofactor, the estrogen receptor is inactive. Different tissues use different cofactors. Some of these cofactors are able to bind to the estrogen receptor/Clomid complex, but others are blocked due to the change in shape. The result is that in some tissues Clomid acts as an antagonist - The cofactor used in that tissue cannot bind and so the receptor remains inactive - And in others Clomid acts as an agonist (activator), because the cofactors used in that tissue are able to bind.

Applications:

Clomifene or clomiphene (USAN) (also known as Clomifert), marketed as Clomid, is a selective estrogen receptor modulator (SERM) that increases production of gonadotropins by inhibiting negative feedback on the hypothalamus.  

It is used mainly in female infertility, in turn mainly as ovulation induction to reverse oligoovulation or anovulation such as in infertility in polycystic ovary syndrome, as well as being used for ovarian hyperstimulation, such as part of an in vitro fertilization procedure. Clomifene citrate is marketed under various trade names including Clomid, Serophene, and Milophene. Prohibited use in sports and use in bodybuilding 

Clomifene is commonly used by male anabolic steroid users to bind the estrogen receptors in their bodies, thereby blocking the effects of estrogen, such as gynecomastia. It also restores the body’s natural production of testosterone. It is commonly used as a “recovery drug” and taken toward the end of a steroid cycle. It is included on the World Anti-Doping Agency list of illegal doping agents in sport

Specifications :

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