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|Appearence:||White Powder||HS Code:||2937190090|
|Density:||1.322 G/cm3||Flash Point:||802.7 ° C|
|Appearance:||White Powder||Solubility:||Soluble In Water And 1% Acetic Acid Conforms|
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CAS 189691-06-3 Bremelanotide Sexual Disorders Polypeptides Bremelanotide PT-141
PT-141 Basic Info.
Molecular Formula: C50H68N14O10
Molecular Weight: 1025.16
Appearance: White powder
Solubility: Soluble in water and 1% acetic acid Conforms
Specifical Optical Rotation: -50°~-60°(c=1,1%HAc) -55.65°
Peptide Purity (By HPLC) ≥ 98.0% by area integration 99.67%
PT-141(Bremelanotide)is the first of a new class of drugs called melanocortin agonists being developed to treat sexual dysfunction. The mechanism of action of PT-141 (Bremelanotide)may offer significant safety and efficacy benefits over currently available products because it acts on the pathway that controls sexual function without acting directly on the vascular system.
PT-141 (Bremelanotide) is the first of a new class of drugs called melanocortin agonists being developed to treat sexual dysfunction.The mechanism of action of PT-141 (Bremelanotide) may offer significant safety and efficacy benefits over currently available products because it acts on the pathway that controls sexual function without acting directly on the vascular system.Clinical data indicates that PT-141 (Bremelanotide) may be effective in treating a broad range of patients suffering from ED.The nasal formulation of PT-141 (Bremelanotide) being developed is as convenient as oral treatments, is more patient-friendly than invasive treatments for ED, such as injections and trans-urethral pellets, and appears to result in a rapid onset of action
Bremelanotide (PT-141) was developed from Melanotan 2 (MT-II).PT-141 is a metabolite of MT-II that lacks the C-terminal amide function-stripping away tanning properties.
PT-141 is the only synthetic aphrodisiac.Studies have shown Bremelanotide to be effective in treating sexual dysfunction in both men (erectile dysfunction or impotence) and women (sexual arousal disorder).Unlike and other related medications (PDE5s), PT-141 does not act upon the vascular system, but directly through the nervous system (hypothalamus) to increase desire.Cialsare not considered aphrodisiacs as they do not have any direct effect on the libido.However, treatment with PDE5 inhibitors and PT-141 are known to have a synergistic effect.
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