50-56-6 Oxytocin Acetate Pharmaceutical Steroids Powder For Hasten Parturition

50-56-6 Oxytocin Acetate Pharmaceutical Steroids Powder For Hasten Parturition

Quck Details:
 

Oxytocin Acetate

Alias:Atonin,Endopituirina,Orasthin,Oxytocinum,Partocon,Pitocin,Piton,Pitupartin,Utedrin,Uteracon

Cas No.: 50-56-6

EINECS : 200-048-4

Molecular Formula: C43H66N12O12S2

Molecular Weight: 1007.19

Purity (HPLC): 98.0%min.

Appearance: White powder

Single Impurity (HPLC): 1.0%max

Amino Acid Composition: ±10% of theoretical

Peptide Content (N%): >80.0%

Water Content(Karl Fischer): <6.0%

Acetate Content(HPIC): <12.0%

MS(ESI): Consistent

Mass Balance: 95.0~105.0%

Grade : Pharmaceutical Grade

Storage: Closed, below 2 ~ 8℃ preservation

Usage : For induction of labor, postpartum oxytocin, and abortion due to uterine atony or retraction caused by the bad uterus bleeding; understand the placental function reserve (oxytocin challenge test); nasal drops can promote milk ejection.

Description:

The oxytocin system is well-known for creating a bond between a mother and her newborn baby, and oxytocin is a lead drug candidate for treating social deficits in autism. Getting synthetic oxytocin into the brain, however, is challenging because of a blood-brain barrier. In this new study, lead researchers Meera Modi, PhD, and Larry Young, PhD, demonstrated for the first time the potential of oxytocin-releasing drugs to activate the social brain, to create bonds and, they believe, to possibly treat social deficits in psychiatric disorders. Meera, who is now at Pfizer, was a graduate student at the Yerkes Research Center when she worked with Young on this research. Young is division chief of Behavioral Neuroscience and Psychiatric Disorders at the Yerkes National Primate Research Center, William P. Timmie professor in the Emory School of Medicine Department of Psychiatry, director of the Center for Translational Social Neuroscience at Emory and principal investigator and director of the NIH Silvio O. Conte Center at Emory.

Oxytocin is a relatively short polypeptide hormone composed of nine amino acids. It is produced primarily in the hypothalamus and acts as a neurotransmitter in the brain. Best known for its role in female reproduction, it is actually found in both male and female mammals.

Unlike most hormones, oxytocin is produced in nerve cells rather than glandular cells. It is primarily produced in the hypothalamus, where sensory nerves stimulate the nerve cells to promote its secretion. This electrical activity causes the hormone to bind to a substance in the pituitary gland known as neurophysin I. It is then released from the posterior lobe of the pituitary gland into the bloodstream, where it then reaches its destination through a process known as neuroendocrine secretion. Alternately, it may leave the hypothalamus to then be distributed to other parts of the brain and spinal cord, and attach to receptors to influence behavior and physiology.

Applications:
 
This hormone plays a major role in female reproduction. First, it is released into the bloodstream as a result of increased uterine, cervical, and vaginal stimulation during childbirth. It then serves to promote contractions of the smooth muscle tissue of the uterus during and after labor, promoting a more rapid childbirth. Medical professionals also sometimes administer it intravenously to induce labor or strengthen contractions. After childbirth, the hormone continues to promote contraction of the uterus, helping to prevent hemorrhaging as well as helping to return the uterus to its pre-gravid state. During childbirth, oxytocin may even cause the involuntary ejection of milk, a reflex known as Ferguson's reflex.
 
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